Vice President JD Vance, Health and Human Services Secretary Robert F. Kennedy Jr., and former heavyweight boxing champion Mike Tyson are set to headline the second Make America Healthy Again (MAHA) Summit in Washington, D.C., on Tuesday. The event, which brings together administration officials, health advocates, and conservative allies, is designed to spotlight the movement's policy victories and lay out its agenda for the coming year.

The summit will close with a “fireside chat” between Vance and Kennedy, according to the event agenda. Organizers told Politico that the conversation will focus on “MAHA’s accomplishments, its regulatory reform agenda, and its priorities for the year ahead.” In a post on X on Monday, Vance wrote: “Since January 2025, thanks to the work of @SecKennedy and the team over at @HHSGov, we have been fulfilling that promise to the American people, and the great MAHA movement. Tune in tomorrow to hear more about the great work being done, and what is coming in the future to secure a stronger nation full of healthier Americans.”

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Kennedy’s wife, actress Cheryl Hines, best known for her role on “Curb Your Enthusiasm,” is scheduled to precede her husband and the vice president with an “exciting announcement,” per the agenda.

Tyson, a longtime friend of President Donald Trump, will participate in a panel on the “MAHA athlete.” He appeared in a Super Bowl ad earlier this year promoting the MAHA campaign and urging Americans to eat “real food.” The athlete-focused session also features former NASCAR driver Danica Patrick, UFC President Dana White, and Russell Cook, co-founder and president of fitness app FitOn. Tyson’s relationship with Trump dates back to the 1980s, when Trump served as his business adviser. Trump later defended Tyson after his 1992 rape conviction and appeared at his first fight after prison, against Peter McNeeley in 1995.

Other notable speakers include comedian Russell Brand, who will moderate a discussion with CMS Administrator Mehmet Oz and HHS chief counselor Chris Klomp on reforms to the Centers for Medicare and Medicaid Services. Brand, a supporter of the MAHA movement, is set to stand trial in the UK next month on charges of rape and sexual assault; he has denied any wrongdoing.

Cabinet members joining the summit include Agriculture Secretary Brooke Rollins and EPA Administrator Lee Zeldin. Rollins will participate in a “fireside chat” with Ohalo Genetics CEO Daniel Friedberg on “securing America’s food supply and environmental innovation,” while Zeldin will join a panel moderated by summit organizer Tony Lyons on “modernizing MAHA regulation.”

Corporate representation includes Walmart senior vice president Scott Morris, Sweetgreen CEO Jonathan Neman, and Steak ’n’ Shake’s chief MAHA officer Michael Boes, who will discuss “real food at scale.” Boes previously served as a senior HHS adviser before joining the restaurant chain. Walmart is among the summit’s sponsors, along with Anthropic, OpenAI, Noom, Hims & Hers, Helus Pharma, and Wild Alaskan Company.

The summit comes as the Trump administration seeks to cement the MAHA movement as a durable political force ahead of the November midterm elections, where control of Congress could hinge on health policy messaging. Organizer Tony Lyons has urged MAHA supporters to vote Republican in November, warning that a Democratic Congress could complicate Kennedy’s agenda. Trump has already deployed Kennedy to key battleground House districts to promote the initiative, and a strong MAHA-aligned voting bloc could give the president more leverage to push his health priorities.

As the administration continues to roll out regulatory changes, the summit serves as both a progress report and a rallying cry for the movement’s base.