President Donald Trump is set to hold a White House event Thursday afternoon focused on health care affordability, where he is expected to unveil a new pricing agreement with pharmaceutical company Regeneron. The deal, confirmed by White House press secretary Karoline Leavitt, is the 17th such accord under the administration’s “most favored nation” initiative, which seeks to lower drug costs by tying U.S. prices to those paid by other developed countries.

The event, scheduled to begin at 3 p.m. EDT, comes as the Trump administration continues to push for more transparency and competition in the pharmaceutical market. The Regeneron deal is part of a broader strategy that has already secured pricing concessions from major drug manufacturers, though critics argue the approach may limit access to certain medications.

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Trump has also promoted his TrumpRX platform, a direct-to-consumer website that offers discounts on more than 40 prescription drugs treating a range of conditions. The platform, which launched earlier this year, is designed to help patients compare prices and find lower-cost options without insurance.

This latest announcement dovetails with other administration efforts to reshape health policy, including a recent move to reclassify medical marijuana, easing federal restrictions that had long hindered research and access. The reclassification has drawn bipartisan praise, though some lawmakers say more comprehensive reform is needed.

However, the healthcare push is unfolding against a backdrop of broader political turbulence. The White House has faced a series of senior staff departures, with five top officials exiting in the past six weeks alone, raising questions about administrative stability. Meanwhile, a recent poll found that 57% of Americans believe the Supreme Court is avoiding rulings that Trump would openly defy, underscoring the tense relationship between the executive and judicial branches.

Trump’s focus on drug pricing also comes as his approval ratings remain under pressure from multiple fronts, including the ongoing fallout from military engagements abroad. Political commentator Bill O’Reilly recently argued that Trump needs a clear victory in Iran to salvage his approval numbers amid the war’s domestic consequences.

The event will be livestreamed on the White House’s official channels. No other speakers have been confirmed, though administration officials are expected to provide additional details on the Regeneron agreement following the president’s remarks.